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Mr. and Mrs. Smith Season 2 Starts Production with New Leads

Published 13 April 2026

Production has begun on the second season of Prime Video's spy thriller series Mr. and Mrs. Smith, featuring a new pair of leads in an anthology-style format that shifts away from the first season's central characters.

Talia Ryder, known for her roles in films such as Never Rarely Sometimes Always and West Side Story, has stepped into the role of Jane Smith, replacing Sophie Thatcher, who had been in negotiations for the part. Ryder will star opposite Mark Eydelshteyn, recognized for his performance in the 2024 film Anora, as John Smith. The casting change stems from scheduling conflicts for Thatcher, tied to her commitments on the final season of Yellowjackets, following a production delay that pushed filming from its original fall 2025 target.

The series, a reimagining of the 2005 film starring Brad Pitt and Angelina Jolie, follows strangers recruited by a secretive spy agency and paired as undercover married spies under the aliases John and Jane Smith. While the first season centered on Donald Glover as John and Maya Erskine as Jane, navigating espionage missions that blurred into real emotions, the second season introduces a fresh duo. Glover and Erskine, who will not...

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