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Joe Manganiello Details Surgery and Seven-Year Illness

Published 16 October 2026

Actor Joe Manganiello says he lost 60 pounds in the two weeks after surgery to remove his large intestine, sharing hospital and recovery photographs on Instagram as he recounted a seven-year illness that he says affected multiple parts of his body. In a post on October 15, Manganiello described the images as showing his hospitalization, an ostomy bag and his abdomen after a later operation reconnected his digestive tract and removed the bag. He also shared a photograph of his face, saying he experienced numerous skin conditions during the years he was sick. The account of his weight loss and medical history comes from Manganiello’s own post; the reports supplied do not include medical records independently confirming those details. Manganiello’s memoir, Bloodlines, released October 13, describes years of illness involving his skin, thyroid, eyes, lungs and digestive system. One account says the illness remains undiagnosed. The supplied material does not establish a medical cause for his condition. In the memoir, Manganiello recounts that he became seriously ill in 2016 and underwent emergency surgery. He credits his then-wife, Sofía Vergara, with authorizing the removal of his...

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