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Applegate pledges continued MS advocacy after misdiagnosis

Published 27 October 2026

Christina Applegate says she will continue advocating for people with multiple sclerosis, despite learning that she was misdiagnosed with the condition. On her podcast MeSsy, she told listeners she still feels part of the MS community and intends to speak on its behalf. Applegate said her connection to people with MS remains important to her, even though she does not have the disease. She co-hosts MeSsy with Jamie-Lynn Sigler, who has publicly discussed living with MS. Applegate said she had grown close to the podcast’s listeners and friends with the condition. Her renewed message of support comes as she continues to describe significant health problems. Applegate said her symptoms have not gone away since doctors told her she does not have MS, and that some aspects of her health have worsened. She said she does not know what is causing them. In an account of her mobility, Applegate said it took her 10 minutes to get out of bed and stand, and that she nearly could not walk to the bathroom. She also said a walker was beside her bed. Those details were her description of her experience; the reports do not establish a new diagnosis or an explanation for the symptoms. Applegate...

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