Oklo Partners with NVIDIA, Los Alamos on AI for Nuclear Fuels

Oklo Inc., a nuclear energy startup, announced a partnership on April 23, 2026, with NVIDIA Corp. and Los Alamos National Laboratory to develop artificial intelligence models for validating plutonium-bearing fuels in advanced reactors, aiming to power AI data centers at the New Mexico laboratory.

The collaboration integrates Oklo's sodium-fast reactor technology, known as the Pluto model, with NVIDIA's high-performance computing and AI tools, and the laboratory's expertise in nuclear materials science. Initial projects will focus on physics- and chemistry-based AI simulations for fuel validation, materials fabrication research, and studies on grid reliability for nuclear-powered AI facilities. This effort supports the U.S. Department of Energy's Genesis Mission, a program across 17 national laboratories that accelerates energy innovations using advanced computing, including AI and quantum platforms.

"This agreement brings together reactor deployment, high-performance compute, and world-class fuel and materials science expertise," said Jacob DeWitte, Oklo's co-founder and chief executive officer. He added that the work will advance plutonium-bearing fuel development for the Pluto...