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No. 20 Louisville Hosts Clemson in ACC Football Game

Published 14 November 2025

The No. 20 Louisville Cardinals host the Clemson Tigers in an ACC college football matchup on Friday night at L&N Federal Credit Union Stadium in Louisville, Kentucky, with kickoff set for 7:30 p.m. ET on ESPN. Both teams enter the game seeking momentum late in the regular season, as Louisville aims to rebound from a recent setback and Clemson fights to secure bowl eligibility.

Louisville, with a 7-2 overall record and 4-2 mark in conference play, suffered a 29-26 overtime loss to California in Week 11, a result that dimmed their prospects for the ACC Championship game. Despite the defeat, the Cardinals remain a strong contender, ranking 26th nationally in overall performance metrics, with a solid offense at No. 37 and defense at No. 27. They have won three of their last four games prior to the California matchup and will look to leverage their home-field advantage. Key contributors include wide receiver Caullin Lacy, who leads the ACC with 128.6 all-purpose yards per game and serves as the team's primary slot receiver, kick returner, and punt returner. Linebacker T.J. Quinn anchors the defense with 67 tackles and two interceptions this season.

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