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Markets

Murray inactive, Brissett to start for Cardinals against Colts

Published 12 October 2025

Kyler Murray will not play Sunday as the Arizona Cardinals travel to Indianapolis after being placed on the inactive list because of a foot injury sustained in last week's game against the Tennessee Titans, the team announced shortly before kickoff. Veteran Jacoby Brissett will start for Arizona, which has dropped three straight games and sits at 2-3.

Murray injured his foot late in the Cardinals' 22-21 loss to Tennessee when a shotgun snap struck him in the face, contributing to a fumble that played into a fourth-quarter collapse. He missed practice on Wednesday and Thursday, returned on a limited basis Friday, and was ultimately declared inactive before the matchup at Lucas Oil Stadium. Head coach Jonathan Gannon had said earlier in the week that the team would "take it day by day" with Murray's health.

Medical evaluations have characterized the problem as a midfoot sprain, described by league sources as a version of a Lisfranc injury. Club and league medical personnel indicated the injury could require more than a week of recovery to avoid aggravation, raising the possibility of a multiweek absence for Atlanta's starting quarterback.

Murray has started every game for the...

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