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Michigan-Oklahoma Headlines Week 2 College Football

Published 8 September 2025

College football moves into Week 2 on Saturday with one clear national headliner and a string of high‑stakes regional showdowns after a chaotic opening weekend that produced several upsets and a reshuffling of the early polls. The marquee matchup pits No. 15 Michigan at No. 18 Oklahoma at 7:30 p.m. Eastern in Norman, while a heated in‑state rivalry between No. 16 Iowa State and Iowa kicks off at noon at Jack Trice Stadium. Other notable games include top‑ranked Ohio State hosting Grambling State and No. 13 Florida welcoming South Florida to The Swamp.

Michigan at Oklahoma is the only meeting of two ranked teams this week and carries outsized significance for both programs. Freshman Bryce Underwood makes his second collegiate start for Michigan against a Sooners defense coached by Brent Venables, while Oklahoma counters with transfer quarterback John Mateer, who opened his OU career with 392 yards and multiple scores. The game will be televised nationally on ABC with College GameDay on site in Norman, underscoring its status as the weekend focal point.

The CyHawk rivalry in Ames features a Cyclones team riding momentum after a 55‑7 win over South Dakota and a Week 0 upset of...

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