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LSU hosting South Carolina as 10-point favorite in primetime

Published 11 October 2025

LSU will host South Carolina on Saturday night in Baton Rouge as the Tigers open a favored line of about 10 points in a matchup between a 4-1 top-15 team and a 3-2 underdog. Kickoff at Tiger Stadium is scheduled for 7:45 p.m. Eastern on Oct. 11 and the game will be televised on the SEC Network. Major sportsbooks opened South Carolina as roughly a 10-point underdog, with some books listing LSU at 10 to 10.5 points.

Both teams come into the game following a bye week. LSU, ranked No. 11, lost 24-19 at Ole Miss in its most recent outing and is seeking a rebound at home. The Tigers opened the season with signature wins over Clemson and Florida that helped their College Football Playoff profile, but have otherwise produced a streak of modest scoring, failing to top 23 points in four of five games. South Carolina enters off a 35-13 home victory over Kentucky and has alternated strong and uneven stretches, standing 3-2 on the year after early conference losses to Vanderbilt and Missouri.

The matchup will put two of the league's most discussed quarterbacks on the same field. LSU starter Garrett Nussmeier has thrown for more yards and attempted more passes than any SEC quarterback this...

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