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Leticia Paul dies after anaphylactic reaction to CT contrast dye

Published 25 August 2025

A 22-year-old law graduate died less than a day after suffering a severe allergic reaction to a contrast dye used during a routine CT scan at a hospital in Rio do Sul, in southern Brazil. Leticia Paul, who had recently completed her law degree and was pursuing postgraduate studies in Law and Real Estate, went into anaphylactic shock after the iodinated contrast agent was administered for the scan at Alto Vale Regional Hospital. She was intubated at the hospital and died within 24 hours of the procedure, drawing attention to the rare but serious risks associated with contrast media used in medical imaging.

Paul, a resident of Lontras, had a history of kidney stones and was undergoing the scan as part of a routine check. Her family described a young woman who loved her studies and had been dedicated to her legal education. The hospital issued condolences to the family and said that all procedures were performed in accordance with established clinical protocols, while reaffirming its commitment to ethics, transparency, and patient safety.

Medical imaging often uses contrast agents to improve the visibility of organs and tissues. The dye ingested or injected before CT and MRI scans...

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