Joe Manganiello to Reveal Health Crisis and Amputation

Actor Joe Manganiello has revealed a severe, years-long health crisis that nearly killed him and led to a lifesaving amputation, details he will share in a memoir scheduled for release on October 13. The 49-year-old star of "True Blood" and "Magic Mike" described a seven-year battle with a cascade of autoimmune illnesses that attacked his skin, thyroid, eyes, lungs, and digestive system, leaving him in chronic pain and facing multiple near-death experiences.

According to the official synopsis from publisher Simon & Schuster, doctors struggled to explain why his body was failing him. With few clear answers from conventional medicine, Manganiello embarked on a global quest for healing that took him beyond traditional treatment. His search involved exploring spirituality, genealogy, and ritual, including work with shamans, pagan practices, and ancient myths. This journey also led him to investigate his family history, where he uncovered stories of ancestors who survived the Armenian genocide and relatives who lived with chronic illness.

In a statement, Manganiello called the period the most brutally difficult time of his life, one he would not wish on his worst enemy, but also his...