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Grey's Anatomy Episode 3 centers on a lung transplant and Bailey

Published 24 October 2025

Grey's Anatomy returned to ABC on Thursday, Oct. 23 with Season 22, Episode 3, titled Between Two Lungs, which centers on a high risk living donor lung transplant that tests the surgical team at Grey Sloan Memorial Hospital while Dr. Miranda Bailey manages a separate trauma patient whose care hangs in the balance. The episode aired at 10 p.m. Eastern and is available to stream the next day on Hulu; live streaming options include services that offer trial periods or paid subscriptions.

The hour pushed several storylines forward. The transplant storyline placed the show's surgical leads under intense professional and emotional pressure and prompted debate among staff about the best course for the donor and recipient. Bailey faced a critical trauma case with rapidly changing prognoses, forcing difficult triage and treatment decisions. Returning guest stars Scott Speedman and Sophia Bush appeared in the episode; Speedman's character took a central role in preparing for the lung transplant, while Bush's character intersected with Teddy Altman in a scene that opened a new romantic possibility as Teddy adjusts to separation from Owen Hunt.

Episode 3 builds on the season premiere's...

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