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Markets

Colts Host Titans as AFC South Lead on the Line

Published 26 October 2025

The Indianapolis Colts, riding a three-game winning streak and the league's top scoring offense, will host the struggling Tennessee Titans on Sunday at Lucas Oil Stadium in Indianapolis. The game is scheduled to start at 4:25 p.m. Eastern and will be televised on CBS. Oddsmakers have installed the Colts as about two-touchdown favorites after Indianapolis beat Tennessee 41-20 in their first meeting this season.

Indianapolis enters Week 8 atop the AFC South and leading the NFL in scoring at roughly 33 points per game. Quarterback Daniel Jones has been a consistent producer in the passing attack while running back Jonathan Taylor leads the league in rushing with 697 yards and 10 rushing touchdowns. The Colts most recently won 38-24 at the Los Angeles Chargers, a game in which Taylor scored three times and Jones threw for 288 yards and two touchdowns.

Tennessee, by contrast, is 1-6 and has struggled to sustain offense. The Titans were beaten 31-13 by the New England Patriots last week, a game in which rookie quarterback Cam Ward completed a strong percentage of passes but also took multiple sacks and fumbled. Tennessee ranks near the bottom in points and yards per play, and its run...

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