49ers vs Cardinals: Purdy, Pearsall Return

The San Francisco 49ers will face the Arizona Cardinals in a crucial NFC West matchup on Sunday, November 16, 2025, at State Farm Stadium in Glendale, Arizona, with kickoff set for 4:05 p.m. ET on FOX. The game carries added significance for the 49ers, who welcome back quarterback Brock Purdy and wide receiver Ricky Pearsall from injuries, bolstering an offense that has managed without them through backup quarterback Mac Jones's steady play.

Purdy, sidelined for six games due to a toe injury first sustained in the season opener, is expected to start after full participation in practices this week. He has appeared in just two games this season, completing 65.8 percent of his passes for 586 yards and four touchdowns. Head coach Kyle Shanahan expressed optimism about Purdy's readiness, noting the quarterback's improved movement and accuracy in recent sessions. "You can just feel it," Shanahan said. "A guy you've been around for a while, like I have Brock, you can just feel how the ball comes off, how he moves, how he reacts." Pearsall, out for the past six games with a knee injury, also cleared the injury report after limited practice earlier in the week. Before his setback, the...