49ers' McCaffrey Questionable with Back Injury vs. Titans

San Francisco 49ers running back Christian McCaffrey has been added to the injury report as questionable with a back issue ahead of Sunday's home game against the Tennessee Titans at Levi's Stadium. The designation, announced Saturday, comes after a week of varying practice participation for the star player, who has been central to the team's 9-4 record and playoff push in the NFC.

McCaffrey sat out Wednesday's practice, which served as a rest day for veterans, and was limited Thursday due to an illness. He returned as a full participant Friday, initially without a game status. The back injury marks the first official designation for McCaffrey since Week 1, when he overcame a preseason calf issue to start in a victory over the Seattle Seahawks. Officials with the 49ers have not provided further details on the back problem, but early reports suggested the Thursday limitation stemmed from illness rather than a lower-body setback from last season.

Through 13 games this season, McCaffrey has carried the ball 237 times for 849 yards and eight touchdowns while catching 85 passes for 806 yards and five scores, totaling 1,655 yards from scrimmage and 13 touchdowns. He leads the NFL with...