49ers DE Bosa expected for season opener

San Francisco 49ers defensive end Nick Bosa is expected to play in the team's season opener against the Los Angeles Rams in Melbourne, Australia, on Friday, September 11, 2026. Defensive coordinator Raheem Morris confirmed Bosa's availability, stating, "He's going out there. We're not trying to hide that." Bosa, 28, has been sidelined since sustaining a season-ending ACL tear in his right knee on September 21, 2025. He underwent surgery on September 26, 2025. After returning to full team practice sessions on September 2, 2026, Bosa experienced soreness and tendinitis, leading the team to manage his workload. He participated in unpadded practice last week and was seen suited up ahead of a practice open to reporters on Monday, September 7, 2026, indicating the team is being cautious. Bosa is entering his eighth NFL season and has been a highly productive pass rusher. He has recorded 64.5 sacks in 85 career games and won the AP NFL Defensive Player of the Year award in 2022. His return is crucial for a 49ers pass rush that finished last in the NFL with 20 sacks in the 2025 season. Tight end George Kittle is also trending toward playing in the opener.